어벤져스의 패배 이후 지구는 초토화됐고 남은 절반의 사람들은 정신적 고통을 호소하며 하루하루를 근근이 버텨나간다. 와칸다에서 싸우다 생존한 히어로들과 우주의 타이탄 행성에서 싸우다 생존한 히어로들이 뿔뿔이 흩어졌는데, 아이언맨과 네뷸라는 우주를 떠돌고 있고 지구에 남아 있는 어벤져스 멤버들은 닉 퓨리가 마지막에 신호를 보내다 만 송신기만 들여다보며 혹시 모를 우주의 응답을 기다리는 중이다. 애초 히어로의 삶을 잠시 내려놓고 가족과 시간을 보내던 호크아이 역시 헤아릴 수 없는 마음의 상처를 입은 채 사라지고 마는데...
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Robert Downey Jr.
Tony Stark / Iron Man
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Chris Evans
Steve Rogers / Captain America
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Mark Ruffalo
Bruce Banner / Hulk
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Chris Hemsworth
Thor Odinson
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Scarlett Johansson
Natasha Romanoff / Black Widow
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Jeremy Renner
Clint Barton / Hawkeye
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Don Cheadle
James Rhodes / War Machine
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Paul Rudd
Scott Lang / Ant-Man
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Chadwick Boseman
T'Challa / Black Panther
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Benedict Cumberbatch
Stephen Strange / Doctor Strange
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Brie Larson
Carol Danvers / Captain Marvel
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Tom Holland
Peter Parker / Spider-Man
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Karen Gillan
Nebula
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Zoe Saldana
Gamora
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Evangeline Lilly
Hope Van Dyne / Wasp
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Tessa Thompson
Valkyrie
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Rene Russo
Frigga
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Elizabeth Olsen
Wanda Maximoff / Scarlet Witch
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Anthony Mackie
Sam Wilson / Falcon
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Sebastian Stan
Bucky Barnes / Winter Soldier
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Tom Hiddleston
Loki
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Danai Gurira
Okoye
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Benedict Wong
Wong
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Pom Klementieff
Mantis
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Dave Bautista
Drax
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Letitia Wright
Shuri
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John Slattery
Howard Stark
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Tilda Swinton
The Ancient One
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Cobie Smulders
Maria Hill
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Jon Favreau
Harold 'Happy' Hogan
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Hayley Atwell
Peggy Carter
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Natalie Portman
Jane Foster
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Marisa Tomei
Aunt May
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Taika Waititi
Korg (voice)
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Angela Bassett
Ramonda
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Michael Douglas
Dr. Hank Pym
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Michelle Pfeiffer
Janet Van Dyne
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William Hurt
Thaddeus 'Thunderbolt' Ross
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Vin Diesel
Groot (voice)
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Bradley Cooper
Rocket (voice)
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Robert Redford
Alexander Pierce
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Gwyneth Paltrow
Pepper Potts
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Chris Pratt
Peter Quill / Star-Lord
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Samuel L. Jackson
Nick Fury
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Josh Brolin
Thanos
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Emma Fuhrmann
Cassie Lang
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Sean Gunn
On-Set Rocket / Kraglin
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Winston Duke
M'Baku
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Linda Cardellini
Laura Barton
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Maximiliano Hernández
Agent Sitwell
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Frank Grillo
Brock Rumlow
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Hiroyuki Sanada
Akihiko
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Tom Vaughan-Lawlor
Ebony Maw
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James D'Arcy
Jarvis
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Jacob Batalon
Ned
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Lexi Rabe
Morgan Stark
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Ross Marquand
Johann Schmidt / Red Skull / Stonekeeper
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Joe Russo
Grieving Man
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Michael James Shaw
Corvus Glaive
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Terry Notary
On-set Groot / Cull Obsidian
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Kerry Condon
F.R.I.D.A.Y. (voice)
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Ben Sakamoto
Cooper Barton
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Ava Russo
Lila Barton
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Cade Woodward
Nathaniel Barton
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Stan Lee
Driver
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Yvette Nicole Brown
S.H.I.E.L.D. Agent
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Callan Mulvey
Jack Rollins
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Lia Russo
Lia
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Julian Russo
Julian
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Taylor Patterson
Taylor
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Agostino Rosalina
Augie
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Ken Jeong
Security Guard
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Ty Simpkins
Harley Keener
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Jackson A. Dunn
Scott Lang (12 Years Old)
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Lee Moore
Scott Lang (93 Years Old)
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John Michael Morris
Young Hank Pym
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Michael A. Cook
Male S.H.I.E.L.D. Agent
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Brent McGee
Camp Lehigh Guard
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Brian Schaeffer
Military Police
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Jamie Wedel
Drill Sergeant
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Anthony G Breed
Young Stan Lee Double
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Erica Ribley
Car Girl
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Monique Ganderton
On-set Proxima Midnight
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Jim Starlin
Support Group Man #1
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Jimmy Ray Pickens
Support Group Man #2
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Hye Jin Jang
Japanese Girl
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Russell Bobbitt
Diner Owner
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Jack Champion
Kid on Bike
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Sam Hargrave
New Asgard Truck Driver
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Patrick Gorman
Old Steve Rogers Double
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Aaron Lazar
Doctor Strange Double
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Robert Pralgo
Thanos Reader
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Tom Wisdom
Loki Reader
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John Posey
Alexander Pierce Reader
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Ameenah Kaplan
Gamora Reader
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Olaniyan Thurmon
Teenage Groot Reader
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Mike Lutz
On-set Reader #2
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Mahesh Babu
Test
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Timothy Carr
Soldier in Fatigues (uncredited)
